Screening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists

Pathways modulating glucose homeostasis independently of insulin would open new avenues to combat insulin resistance and diabetes. Here, we report the establishment, characterization, and use of a vertebrate ‘insulin-free’ model to identify insulin-independent modulators of glucose metabolism. insul...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Mullapudi, Sri Teja, Helker, Christian SM, Boezio, Giulia LM, Maischein, Hans-Martin, Sokol, Anna M, Guenther, Stefan, Matsuda, Hiroki, Kubicek, Stefan, Graumann, Johannes, Yang, Yu Hsuan Carol, Stainier, Didier YR
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300353/
https://ncbi.nlm.nih.gov/pubmed/30520733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42209
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