A paradoxical method to enhance compensatory lung growth: Utilizing a VEGF inhibitor

Exogenous vascular endothelial growth factor (VEGF) accelerates compensatory lung growth (CLG) in mice after unilateral pneumonectomy. In this study, we unexpectedly discovered a method to enhance CLG with a VEGF inhibitor, soluble VEGFR1. Eight-week-old C57BL/6 male mice underwent left pneumonectom...

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Bibliographic Details
Published in:PLoS One
Main Authors: Dao, Duy T., Anez-Bustillos, Lorenzo, Jabbouri, Sahir S., Pan, Amy, Kishikawa, Hiroko, Mitchell, Paul D., Fell, Gillian L., Baker, Meredith A., Watnick, Randolph S., Chen, Hong, Rogers, Michael S., Bielenberg, Diane R., Puder, Mark
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300284/
https://ncbi.nlm.nih.gov/pubmed/30566445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208579
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