Elevation in lung volume and preventing catastrophic airway closure in asthmatics during bronchoconstriction

BACKGROUND: Asthma exacerbations cause lung hyperinflation, elevation in load to inspiratory muscles, and decreased breathing capacity that, in severe cases, may lead to inspiratory muscle fatigue and respiratory failure. Hyperinflation has been attributed to a passive mechanical origin; a respirato...

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Pubblicato in:PLoS One
Autori principali: Osorio-Valencia, Juan S., Wongviriyawong, Chanikarn, Winkler, Tilo, Kelly, Vanessa J., Harris, Robert S., Venegas, Jose G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300269/
https://ncbi.nlm.nih.gov/pubmed/30566496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208337
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