Elevation in lung volume and preventing catastrophic airway closure in asthmatics during bronchoconstriction

BACKGROUND: Asthma exacerbations cause lung hyperinflation, elevation in load to inspiratory muscles, and decreased breathing capacity that, in severe cases, may lead to inspiratory muscle fatigue and respiratory failure. Hyperinflation has been attributed to a passive mechanical origin; a respirato...

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Publicado en:PLoS One
Autores principales: Osorio-Valencia, Juan S., Wongviriyawong, Chanikarn, Winkler, Tilo, Kelly, Vanessa J., Harris, Robert S., Venegas, Jose G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300269/
https://ncbi.nlm.nih.gov/pubmed/30566496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208337
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