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Elevation in lung volume and preventing catastrophic airway closure in asthmatics during bronchoconstriction

BACKGROUND: Asthma exacerbations cause lung hyperinflation, elevation in load to inspiratory muscles, and decreased breathing capacity that, in severe cases, may lead to inspiratory muscle fatigue and respiratory failure. Hyperinflation has been attributed to a passive mechanical origin; a respirato...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Osorio-Valencia, Juan S., Wongviriyawong, Chanikarn, Winkler, Tilo, Kelly, Vanessa J., Harris, Robert S., Venegas, Jose G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300269/
https://ncbi.nlm.nih.gov/pubmed/30566496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208337
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