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A role for Gic1 and Gic2 in Cdc42 polarization at elevated temperature

The conserved Rho-family GTPase Cdc42 is a master regulator of polarity establishment in many cell types. Cdc42 becomes activated and concentrated in a region of the cell cortex, and recruits a variety of effector proteins to that site. In turn, many effectors participate in regulation of cytoskelet...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Daniels, Christine N., Zyla, Trevin R., Lew, Daniel J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300207/
https://ncbi.nlm.nih.gov/pubmed/30566437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200863
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