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Insulin acts as a repressive factor to inhibit the ability of PAR2 to induce islet cell transdifferentiation

Recently, we showed that pancreatitis in the context of profound β-cell deficiency was sufficient to induce islet cell transdifferentiation. In some circumstances, this effect was sufficient to result in recovery from severe diabetes. More recently, we showed that the molecular mechanism by which pa...

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Bibliografische gegevens
Gepubliceerd in:Islets
Hoofdauteurs: Lee, Seung-Hee, Hao, Ergeng, Scharp, David, Levine, Fred
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300087/
https://ncbi.nlm.nih.gov/pubmed/29723131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2018.1472839
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