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Cell Hashing with barcoded antibodies enables multiplexing and doublet detection for single cell genomics
Despite rapid developments in single cell sequencing, sample-specific batch effects, detection of cell multiplets, and experimental costs remain outstanding challenges. Here, we introduce Cell Hashing, where oligo-tagged antibodies against ubiquitously expressed surface proteins uniquely label cells...
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| Опубликовано в: : | Genome Biol |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6300015/ https://ncbi.nlm.nih.gov/pubmed/30567574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1603-1 |
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