Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [(11)C]DPA-713 PET

The pathophysiology of post-treatment Lyme disease syndrome (PTLDS) may be linked to overactive immunity including aberrant activity of the brain’s resident immune cells, microglia. Here we used [(11)C]DPA-713 and positron emission tomography to quantify the 18 kDa translocator protein, a marker of...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Coughlin, Jennifer M., Yang, Ting, Rebman, Alison W., Bechtold, Kathleen T., Du, Yong, Mathews, William B., Lesniak, Wojciech G., Mihm, Erica A., Frey, Sarah M., Marshall, Erica S., Rosenthal, Hailey B., Reekie, Tristan A., Kassiou, Michael, Dannals, Robert F., Soloski, Mark J., Aucott, John N., Pomper, Martin G.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299943/
https://ncbi.nlm.nih.gov/pubmed/30567544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1381-4
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