Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons

BACKGROUND: Mutations in CHD8, chromodomain helicase DNA-binding protein 8, are among the most replicated and common findings in genetic studies of autism spectrum disorder (ASD). The CHD8 protein is believed to act as a transcriptional regulator by remodeling chromatin structure and recruiting hist...

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Veröffentlicht in:Mol Autism
Hauptverfasser: Xu, Qiong, Liu, Yuan-yuan, Wang, Xiaoming, Tan, Guo-he, Li, Hui-ping, Hulbert, Samuel W., Li, Chun-yang, Hu, Chun-chun, Xiong, Zhi-qi, Xu, Xiu, Jiang, Yong-hui
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299922/
https://ncbi.nlm.nih.gov/pubmed/30574290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-018-0244-2
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