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Lipofuscin accumulation in cortisol producing adenomas with and without PRKACA mutations

The adrenal cortex accumulates lipofuscin granules with age. Lipofuscin accumulation is also seen in adrenocortical tumors associated with Cushing syndrome (CS), particularly those with PRKAR1A mutations, such as in primary pigmented nodular adrenocortical disease (PPNAD). We investigated the presen...

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Detalhes bibliográficos
Publicado no:Horm Metab Res
Main Authors: Angelousi, Anna, Szarek, Eva, Shram, Vincent, Kebebew, Electron, Quezado, Martha, Stratakis, Constantine A
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299839/
https://ncbi.nlm.nih.gov/pubmed/28834963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0043-116385
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