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Immunosuppressive therapy influences the accelerated age-dependent T-helper cell differentiation in systemic lupus erythematosus remission patients

BACKGROUND: CD4(+) T cells are of great importance in the pathogenesis of systemic lupus erythematosus (SLE), as an imbalance between CD4(+) regulatory T cells (Tregs) and CD4(+) responder T cells (Tresps) causes flares of active disease in SLE patients. In this study, we aimed to find the role of a...

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Опубликовано в: :Arthritis Res Ther
Главные авторы: Schaier, Matthias, Gottschalk, Claudius, Uhlmann, Lorenz, Speer, Claudius, Kälble, Florian, Eckstein, Volker, Müller-Tidow, Carsten, Meuer, Stefan, Mahnke, Karsten, Lorenz, Hanns-Martin, Zeier, Martin, Steinborn, Andrea
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299578/
https://ncbi.nlm.nih.gov/pubmed/30563559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1778-6
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