UVB-mediated down-regulation of proteasome in cultured human primary pterygium fibroblasts

BACKGROUND: Pterygium is a condition characterized by epithelial overgrowth of the cornea, inflammatory cell infiltration and an abnormal extracellular matrix accumulation. Chronic UV exposure is considered as a pathogenic factor of this disease. Proteasome is an intracellular multi-subunit protease...

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Veröffentlicht in:BMC Ophthalmol
Hauptverfasser: Aletras, Alexios J., Trilivas, Ioannis, Christopoulou, Maria-Elpida, Drakouli, Sotiria, Georgakopoulos, Constantine D., Pharmakakis, Nikolaos
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299496/
https://ncbi.nlm.nih.gov/pubmed/30563490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-018-0987-8
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