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Human ex vivo 3D bone model recapitulates osteocyte response to metastatic prostate cancer

Prostate cancer (PCa) is the second leading cause of cancer deaths among American men. Unfortunately, there is no cure once the tumor is established within the bone niche. Although osteocytes are master regulators of bone homeostasis and remodeling, their role in supporting PCa metastases remains po...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Choudhary, Saba, Ramasundaram, Poornema, Dziopa, Eugenia, Mannion, Ciaran, Kissin, Yair, Tricoli, Lucas, Albanese, Christopher, Lee, Woo, Zilberberg, Jenny
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299475/
https://ncbi.nlm.nih.gov/pubmed/30568232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36424-x
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