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BPI-9016M, a c-Met inhibitor, suppresses tumor cell growth, migration and invasion of lung adenocarcinoma via miR203-DKK1

Activation of c-Met plays a critical role in tumorigenesis, migration and invasion in lung cancer. Here, we explored the therapeutic efficacy of a novel small-molecule c-Met inhibitor (BPI-9016M) in lung adenocarcinoma and investigated the underlying molecular mechanisms. Method: BPI-9016M, a c-Met...

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Vydáno v:Theranostics
Hlavní autoři: Zhang, Panpan, Li, Shaolei, Lv, Chao, Si, Jiahui, Xiong, Ying, Ding, Lieming, Ma, Yuanyuan, Yang, Yue
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299440/
https://ncbi.nlm.nih.gov/pubmed/30613269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.27667
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