CpaA Is a Glycan-Specific Adamalysin-like Protease Secreted by Acinetobacter baumannii That Inactivates Coagulation Factor XII

Antibiotic-resistant Acinetobacter baumannii is increasingly recognized as a cause of difficult-to-treat nosocomial infections, including pneumonia, wound infections, and bacteremia. Previous studies have demonstrated that the metalloprotease CpaA contributes to virulence and prolongs clotting time...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Waack, Ursula, Warnock, Mark, Yee, Andrew, Huttinger, Zachary, Smith, Sara, Kumar, Ayush, Deroux, Alban, Ginsburg, David, Mobley, Harry L. T., Lawrence, Daniel A., Sandkvist, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299215/
https://ncbi.nlm.nih.gov/pubmed/30563903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01606-18
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