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A Model for Human Islet Transplantation to Immunodeficient Streptozotocin-Induced Diabetic Mice

Streptozotocin (STZ) is a cytotoxic glucose analogue that causes beta cell death and is widely used to induce experimental diabetes in rodents. The sensitivity of beta cells to STZ is species-specific and human beta cells are resistant to STZ. In experimental islet transplantation to rodents, STZ-di...

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Dettagli Bibliografici
Pubblicato in:Cell Transplant
Autori principali: Estil·les, Elisabet, Téllez, Noèlia, Nacher, Montserrat, Montanya, Eduard
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299193/
https://ncbi.nlm.nih.gov/pubmed/30269527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0963689718801006
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