Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome

INTRODUCTION: Pendred syndrome is an autosomal-recessive disease characterized by congenital hearing loss and thyroid goiter. Previously, cell stress susceptibilities were shown to increase in patient-derived cells with intracellular aggregation using an in vitro acute cochlear cell model derived fr...

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Vydáno v:Regen Ther
Hlavní autoři: Hosoya, Makoto, Saeki, Tsubasa, Saegusa, Chika, Matsunaga, Tatsuo, Okano, Hideyuki, Fujioka, Masato, Ogawa, Kaoru
Médium: Artigo
Jazyk:Inglês
Vydáno: Japanese Society for Regenerative Medicine 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299162/
https://ncbi.nlm.nih.gov/pubmed/30581897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reth.2018.11.001
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