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Preventive Leptin Administration Protects Against Sepsis Through Improving Hypotension, Tachycardia, Oxidative Stress Burst, Multiple Organ Dysfunction, and Increasing Survival

Sepsis syndrome is the most important cause of mortality in critically ill patients admitted to intensive care units (ICUs). However, current therapies for its prevention and treatment are still unsatisfactory, and the mortality rate is still high. Non-septic ICU patients are vulnerable to acquire s...

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Bibliographische Detailangaben
Veröffentlicht in:Front Physiol
Hauptverfasser: Vallejos, Alejandro, Olivares, Pedro, Varela, Diego, Echeverria, Cesar, Cabello-Verrugio, Claudio, Pérez-Leighton, Claudio, Simon, Felipe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299116/
https://ncbi.nlm.nih.gov/pubmed/30618812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01800
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