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Extrachromosomal circular elements targeted by CRISPR-Cas in Dehalococcoides mccartyi are linked to mobilization of reductive dehalogenase genes

Dehalococcoides mccartyi are obligate organohalide-respiring bacteria that play an important detoxifying role in the environment. They have small genomes (~1.4 Mb) with a core region interrupted by two high plasticity regions (HPRs) containing dozens of genes encoding reductive dehalogenases involve...

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Dettagli Bibliografici
Pubblicato in:ISME J
Autori principali: Molenda, Olivia, Tang, Shuiquan, Lomheim, Line, Gautam, Vasu K., Lemak, Sofia, Yakunin, Alexander F., Maxwell, Karen L., Edwards, Elizabeth A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299113/
https://ncbi.nlm.nih.gov/pubmed/30104577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41396-018-0254-2
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