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Interleukin 2 modulates thymic-derived regulatory T cell epigenetic landscape
Foxp3(+)CD4(+) regulatory T (T(reg)) cells are essential for preventing fatal autoimmunity and safeguard immune homeostasis in vivo. While expression of the transcription factor Foxp3 and IL-2 signals are both required for the development and function of T(reg) cells, the commitment to the T(reg) ce...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6299086/ https://ncbi.nlm.nih.gov/pubmed/30560927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07806-6 |
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