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The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation

Surface receptor and transporter protein down-regulation is assumed to be exclusively mediated by the canonical multivesicular body (MVB) pathway and ESCRTs (Endosomal Sorting Complexes Required for Transport). However, few surface proteins are known to require ESCRTs for down-regulation, and report...

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Publicat a:Nat Commun
Autors principals: McNally, Erin Kate, Brett, Christopher Leonard
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299085/
https://ncbi.nlm.nih.gov/pubmed/30560896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07734-5
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