HAI Peptide and Backbone Analogs—Validation and Enhancement of Biostability and Bioactivity of BBB Shuttles

Low effectiveness and resistance to treatments are commonplace in disorders of the central nervous system (CNS). These issues concern mainly the blood-brain barrier (BBB), which preserves homeostasis in the brain and protects this organ from toxic molecules and biohazards by regulating transport thr...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Arranz-Gibert, Pol, Prades, Roger, Guixer, Bernat, Guerrero, Simón, Araya, Eyleen, Ciudad, Sonia, Kogan, Marcelo J., Giralt, Ernest, Teixidó, Meritxell
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298966/
https://ncbi.nlm.nih.gov/pubmed/30560894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35938-8
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