Immunogenic particles with a broad antigenic spectrum stimulate cytolytic T cells and offer increased protection against EBV infection ex vivo and in mice

The ubiquitous Epstein-Barr virus (EBV) is the primary cause of infectious mononucleosis and is etiologically linked to the development of several malignancies and autoimmune diseases. EBV has a multifaceted life cycle that comprises virus lytic replication and latency programs. Considering EBV infe...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: van Zyl, Dwain G., Tsai, Ming-Han, Shumilov, Anatoliy, Schneidt, Viktor, Poirey, Rémy, Schlehe, Bettina, Fluhr, Herbert, Mautner, Josef, Delecluse, Henri-Jacques
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298685/
https://ncbi.nlm.nih.gov/pubmed/30521644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007464
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