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Single Nucleotide Variant in Nucleoporin 107 may be Predictive of Sensitivity to Chemotherapy in Patient with Ovarian Cancer

BACKGROUND: Alterations in nuclear pore complex (NPC) genes have been previously associated with response to chemotherapy. By using agnostic exome sequencing, we envisioned that new alleles in NPC genes, predictive of sensitivity to platinum treatment, could be discovered. METHODS: Twenty-two Platin...

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Publicado en:Pharmacogenet Genomics
Autores principales: Alanee, Shaheen, Delfino, Kristin, Wilber, Andrew, Robinson, Kathy, Brard, Laurent, Semaan, Assaad
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298606/
https://ncbi.nlm.nih.gov/pubmed/28562428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000288
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