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Shear stress augments mitochondrial ATP generation that triggers ATP release and Ca(2+) signaling in vascular endothelial cells
Vascular endothelial cells (ECs) sense and transduce hemodynamic shear stress into intracellular biochemical signals, and Ca(2+) signaling plays a critical role in this mechanotransduction, i.e., ECs release ATP in the caveolae in response to shear stress and, in turn, the released ATP activates P2...
Enregistré dans:
| Publié dans: | Am J Physiol Heart Circ Physiol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6297820/ https://ncbi.nlm.nih.gov/pubmed/30141983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00204.2018 |
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