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MYCN is amplified during S phase, and c-myb is involved in controlling MYCN expression and amplification in MYCN-amplified neuroblastoma cell lines

Neuroblastoma derived from primitive sympathetic neural precursors is a common type of solid tumor in infants. MYCN proto-oncogene bHLH transcription factor (MYCN) amplification and 1p36 deletion are important factors associated with the poor prognosis of neuroblastoma. Expression levels of MYCN and...

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: Aygun, Nevim, Altungoz, Oguz
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297758/
https://ncbi.nlm.nih.gov/pubmed/30483774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9686
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