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Streptolysin O derived from Streptococcus pyogenes inhibits RANKL-induced osteoclastogenesis through the NF-κB signaling pathway

Streptococcus pyogenes (GAS) is a clinically significant bacterial strain that causes bacterial arthritis, osteomyelitis and implant infections. Infection complications can lead to serious bone destruction. Osteoclasts, the only type of cell with bone resorption function, participate in this process...

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Publicado en:Mol Med Rep
Main Authors: Yi, Jin, Tang, Ruohui, Yang, Jing, Chen, Yueqi, Fei, Jun
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297742/
https://ncbi.nlm.nih.gov/pubmed/30431141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9662
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