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Pyroglutamic acidosis in association with therapeutic paracetamol use

Long-term use of paracetamol (at therapeutic doses) can cause the accumulation of endogenous organic pyroglutamate, resulting in metabolic acidosis with an elevated anion gap. This occurs in the presence of malnutrition, infection, antibiotic use, renal failure and pregnancy. Given the prevalence of...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Med (Lond)
Hauptverfasser: Hunter, Robert W, Lawson, Cate, Galitsiou, Evangelia, Gifford, Fiona, Neary, John J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal College of Physicians 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297337/
https://ncbi.nlm.nih.gov/pubmed/27927815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7861/clinmedicine.16-6-524
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