aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability

Strict regulation of proliferation is vital for development, whereas unregulated cell proliferation is a fundamental characteristic of cancer. The polarity protein atypical protein kinase C lambda/iota (aPKCλ) is associated with cell proliferation through unknown mechanisms. In endothelial cells, su...

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Publicado no:Nat Commun
Main Authors: Riddell, Meghan, Nakayama, Akiko, Hikita, Takao, Mirzapourshafiyi, Fatemeh, Kawamura, Takuji, Pasha, Ayesha, Li, Mengnan, Masuzawa, Mikio, Looso, Mario, Steinbacher, Tim, Ebnet, Klaus, Potente, Michael, Hirose, Tomonori, Ohno, Shigeo, Fleming, Ingrid, Gattenlöhner, Stefan, Aung, Phyu P., Phung, Thuy, Yamasaki, Osamu, Yanagi, Teruki, Umemura, Hiroshi, Nakayama, Masanori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297234/
https://ncbi.nlm.nih.gov/pubmed/30559384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07739-0
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