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Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR

Experiments with stable isotope tracers such as (13)C and (15)N are increasingly used to gain insights into metabolism. However, mass spectrometric measurements of stable isotope labeling experiments should be corrected for the presence of naturally occurring stable isotopes and for impurities of th...

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Опубликовано в: :Sci Rep
Главные авторы: Heinrich, Paul, Kohler, Christian, Ellmann, Lisa, Kuerner, Paul, Spang, Rainer, Oefner, Peter J., Dettmer, Katja
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297158/
https://ncbi.nlm.nih.gov/pubmed/30559398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36293-4
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