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Varying the rate of intravenous cocaine infusion influences the temporal dynamics of both drug and dopamine concentrations in the striatum

The faster drugs of abuse reach the brain, the greater is the risk of addiction. Even small differences in the rate of drug delivery can influence outcome. Infusing cocaine intravenously over 5 versus 90–100 seconds promotes sensitization to the psychomotor and incentive motivational effects of the...

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Detalhes bibliográficos
Publicado no:Eur J Neurosci
Main Authors: Minogianis, Ellie-Anna, Shams, Waqqas M., Mabrouk, Omar S., Wong, Jenny-Marie T., Brake, Wayne G., Kennedy, Robert T., du Souich, Patrick, Samaha, Anne-Noël
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296906/
https://ncbi.nlm.nih.gov/pubmed/29757478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.13941
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