The role of genomic profiling in adolescents and young adults (AYAs) with advanced cancer participating in Phase I clinical trials

INTRODUCTION: Adolescents and young adults (AYAs) diagnosed with cancer between ages 15-39 years may harbour germline variants associated with cancer predisposition. Such variants represent putative therapeutic targets, as may somatic variants in the tumour. Germline and tumour molecular profiling i...

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Publicado no:Eur J Cancer
Main Authors: McVeigh, Terri Patricia, Sundar, Raghav, Diamantis, Nikolaos, Kaye, Stan B, Banerji, Udai, Lopez, Juanita S, de Bono, Johann, van der Graaf, Winette T, George, Angela J
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296443/
https://ncbi.nlm.nih.gov/pubmed/29614442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2018.02.028
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