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High Mobility Group Box 1 (HMGB1) Predicts Invasion and Poor Prognosis of Glioblastoma Multiforme via Activating AKT Signaling in an Autocrine Pathway

BACKGROUND: As a nuclear protein and a secreted protein, HMGB1 is involved in many cellular processes such as proliferation, transcription, and inflammation. The overexpression of HMGB1 in various types of cancers is reported, but its clinical significance and prognostic value in glioblastoma multif...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Med Sci Monit
Hauptverfasser: Cheng, Peng, Ma, Yun, Gao, Zhiqiang, Duan, Lingling
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Scientific Literature, Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296343/
https://ncbi.nlm.nih.gov/pubmed/30531692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.912104
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