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High Mobility Group Box 1 (HMGB1) Predicts Invasion and Poor Prognosis of Glioblastoma Multiforme via Activating AKT Signaling in an Autocrine Pathway

BACKGROUND: As a nuclear protein and a secreted protein, HMGB1 is involved in many cellular processes such as proliferation, transcription, and inflammation. The overexpression of HMGB1 in various types of cancers is reported, but its clinical significance and prognostic value in glioblastoma multif...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Cheng, Peng, Ma, Yun, Gao, Zhiqiang, Duan, Lingling
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296343/
https://ncbi.nlm.nih.gov/pubmed/30531692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.912104
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