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Topical anesthesia therapy using lidocaine-loaded nanostructured lipid carriers: tocopheryl polyethylene glycol 1000 succinate-modified transdermal delivery system

PURPOSE: Transdermal drug delivery of local anesthetics using lipid nanoparticles could enhance lipophilic drugs permeation through the stratum corneum, improve drug diffusion to deeper skin, and exert good therapeutic effects. The purpose of this study was to engineer a Tocopheryl Polyethylene Glyc...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhao, Xiangju, Sun, Ying, Li, Zhaoguo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296185/
https://ncbi.nlm.nih.gov/pubmed/30587919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S187177
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