Oxidative damage in naturally aged mouse oocytes is exacerbated by dysregulation of proteasomal activity

An increase in oxidative protein damage is a leading contributor to the age-associated decline in oocyte quality. By removing such damaged proteins, the proteasome plays an essential role in maintaining the fidelity of oocyte meiosis. In this study, we established that decreased proteasome activity...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mihalas, Bettina P., Bromfield, Elizabeth G., Sutherland, Jessie M., De Iuliis, Geoffry N., McLaughlin, Eileen A., Aitken, R. John, Nixon, Brett
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295717/
https://ncbi.nlm.nih.gov/pubmed/30305393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005751
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados