Evaluation of microsatellite instability in tumor and tumor marginal samples of sporadic colorectal cancer using mononucleotide markers

Microsatellite instability (MSI) is a unique molecular alteration that is due to a defective DNA mismatch repair (MMR) system. Approximately, 15-20 % of sporadic colorectal cancers (CRC) display MSI. Determination of MSI status in CRC has prognostic and predictive implications. Additionally, detecti...

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Bibliografski detalji
Izdano u:EXCLI J
Glavni autori: Nouri Nojadeh, Jafar, Hashemzadeh, Shahriar, Samadi Kafil, Hossein, Behrouz Sharif, Shahin, Eftekharsadat, Amirtaher, Ghasemnejad, Tohid, Ghojazadeh, Mortaza, Sakhinia, Ebrahim
Format: Artigo
Jezik:Inglês
Izdano: Leibniz Research Centre for Working Environment and Human Factors 2018
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295640/
https://ncbi.nlm.nih.gov/pubmed/30564073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2018-1455
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