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The in vivo dsRNA Cleavage Has Sequence Preference in Insects

Exogenous dsRNA enters the insect body and can induce the RNAi effect only when it is cleaved into siRNA. However, what kinds of base composition are easier to cut and what kinds of siRNA will be produced in vivo is largely unknown. In this study, we found that dsRNA processing into siRNA has sequen...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Guan, Ruobing, Hu, Shaoru, Li, Haichao, Shi, Zhenying, Miao, Xuexia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295558/
https://ncbi.nlm.nih.gov/pubmed/30618790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01768
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