Synthesizing Signaling Pathways from Temporal Phosphoproteomic Data

We present a method for automatically discovering signaling pathways from time-resolved phosphoproteomic data. The Temporal Pathway Synthesizer (TPS) algorithm uses constraint-solving techniques first developed in the context of formal verification to explore paths in an interaction network. It syst...

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Publicado en:Cell Rep
Main Authors: Kӧksal, Ali Sinan, Beck, Kirsten, Cronin, Dylan R., McKenna, Aaron, Camp, Nathan D., Srivastava, Saurabh, MacGilvray, Matthew E., Bodík, Rastislav, Wolf-Yadlin, Alejandro, Fraenkel, Ernest, Fisher, Jasmin, Gitter, Anthony
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295338/
https://ncbi.nlm.nih.gov/pubmed/30257219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.085
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