A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice
In contrast to lower vertebrates, the mammalian heart has limited capacity to regenerate after injury in part due to ineffective reactivation of cardiomyocyte proliferation. We show that the microRNA cluster miR302–367 is important for cardiomyocyte proliferation during development and is sufficient...
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Publicado no: | Sci Transl Med |
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Main Authors: | , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6295313/ https://ncbi.nlm.nih.gov/pubmed/25787764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3010841 |
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