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Targeting resistance to targeted therapies: combating a resilient foe

While the advent of third generation therapies have dramatically changed the treatment paradigm for EGFR mutated lung cancer, resistance to these agents inevitably emerges. Understanding resistance mechanisms and their genomic underpinnings is crucial for developing innovative strategies that are ca...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Devarakonda, Siddhartha, Govindan, Ramaswamy
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295273/
https://ncbi.nlm.nih.gov/pubmed/30352903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3178
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