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Targeting resistance to targeted therapies: combating a resilient foe

While the advent of third generation therapies have dramatically changed the treatment paradigm for EGFR mutated lung cancer, resistance to these agents inevitably emerges. Understanding resistance mechanisms and their genomic underpinnings is crucial for developing innovative strategies that are ca...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Devarakonda, Siddhartha, Govindan, Ramaswamy
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295273/
https://ncbi.nlm.nih.gov/pubmed/30352903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3178
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