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Allenoates in Enantioselective [2+2] Cycloadditions: From a Mechanistic Curiosity to a Stereospecific Transformation

Identification of a novel catalyst–allenoate pair allows enantioselective [2+2] cycloaddition of α-methylstyrene. To understand the origin of selectivity, a detailed mechanistic investigation was conducted. Herein, two competing reaction pathways are proposed, which operate simultaneously and funnel...

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Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Wiest, Johannes. M., Conner, Michael L., Brown, M. Kevin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295144/
https://ncbi.nlm.nih.gov/pubmed/30394735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b10008
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