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Intrinsic cellular chirality regulates left–right symmetry breaking during cardiac looping

The vertebrate body plan is overall symmetrical but left–right (LR) asymmetric in the shape and positioning of internal organs. Although several theories have been proposed, the biophysical mechanisms underlying LR asymmetry are still unclear, especially the role of cell chirality, the LR asymmetry...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Ray, Poulomi, Chin, Amanda S., Worley, Kathryn E., Fan, Jie, Kaur, Gurleen, Wu, Mingfu, Wan, Leo Q.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294912/
https://ncbi.nlm.nih.gov/pubmed/30459275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808052115
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