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Combined functions of two RRMs in Dead-end1 mimic helicase activity to promote nanos1 translation in the germline

Dead-end1 expression is restricted to the vertebrate germline where it is believed to activate translation of mRNAs required to protect and promote that unique lineage. nanos1 is one such germline mRNA whose translation is blocked by a secondary mRNA structure within the ORF. Dead-end1 contains a ca...

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Bibliografiske detaljer
Udgivet i:Mol Reprod Dev
Main Authors: Aguero, Tristan, Jin, Zhigang, Owens, Dawn, Malhotra, Arun, Newman, Karen, Yang, Jing, King, Mary Lou
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294668/
https://ncbi.nlm.nih.gov/pubmed/30230100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.23062
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