Expression of CD25 fluctuates in the leukemia-initiating cell population of CD25-positive AML

CD25 is expressed on leukemic cells in 10–20% cases of acute myeloid leukemia (AML), and its expression is associated with poor prognosis. We reevaluated the relationship between CD25 expression and the leukemia-initiating cell (LIC) properties of AML using a patient-derived xenograft model. We divi...

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Udgivet i:PLoS One
Main Authors: Kageyama, Yuki, Miwa, Hiroshi, Arakawa, Rino, Tawara, Isao, Ohishi, Kohshi, Masuya, Masahiro, Nakase, Kazunori, Katayama, Naoyuki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294374/
https://ncbi.nlm.nih.gov/pubmed/30550585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209295
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