Loading...
β Cell Replacement after Gene Editing of a Neonatal Diabetes-Causing Mutation at the Insulin Locus
Permanent neonatal diabetes mellitus (PNDM) can be caused by insulin mutations. We generated induced pluripotent stem cells from fibroblasts of a patient with PNDM and undetectable insulin at birth due to a homozygous mutation in the translation start site of the insulin gene. Differentiation of mut...
Na minha lista:
| Udgivet i: | Stem Cell Reports |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2018
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294262/ https://ncbi.nlm.nih.gov/pubmed/30503261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.11.006 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|