Increased Calcium Influx through L-type Calcium Channels in Human and Mouse Neural Progenitors Lacking Fragile X Mental Retardation Protein

The absence of FMR1 protein (FMRP) causes fragile X syndrome (FXS) and disturbed FMRP function is implicated in several forms of human psychopathology. We show that intracellular calcium responses to depolarization are augmented in neural progenitors derived from human induced pluripotent stem cells...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Danesi, Claudia, Achuta, Venkat Swaroop, Corcoran, Padraic, Peteri, Ulla-Kaisa, Turconi, Giorgio, Matsui, Nobuaki, Albayrak, Ilyas, Rezov, Veronika, Isaksson, Anders, Castrén, Maija L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294261/
https://ncbi.nlm.nih.gov/pubmed/30503263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.11.003
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