GIT1 contributes to autophagy in osteoclast through disruption of the binding of Beclin1 and Bcl2 under starvation condition

Approximately 10–15% of all bone fractures do not heal properly, causing patient morbidity and additional medical care expenses. Therefore, better mechanism-based fracture repair approaches are needed. In this study, a reduced number of osteoclasts (OCs) and autophagosomes/autolysosomes in OC can be...

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I publikationen:Cell Death Dis
Huvudupphovsmän: Zhao, Shu-Jie, Kong, Fan-Qi, Cai, Wei, Xu, Tao, Zhou, Zhi-Min, Wang, Zi-Bin, Xu, An-Di, Yang, Ya-Qing, Chen, Jian, Tang, Peng-Yu, Wang, Qian, Cheng, Lin, Luo, Yong-Jun, Zhou, Zheng, Li, Lin-Wei, Huang, Yi-Fan, Zhao, Xuan, Yin, Guo-Yong, Xue, Ming-Xin, Fan, Jin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294144/
https://ncbi.nlm.nih.gov/pubmed/30546041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1256-8
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