HISTOLOGIC PATTERN OF INVASION AND EPITHELIAL-MESENCHYMAL PHENOTYPE PREDICT PROGNOSIS IN SQUAMOUS CARCINOMA OF THE HEAD AND NECK.

INTRODUCTION: Disruption of E-cadherin function and increased expression of vimentin and the transcriptional oncogene, SOX2, are thought to characterize epithelial to mesenchymal transition (EMT) in HNSCC that contributes to invasive and metastatic behavior. To determine if such changes relate to pr...

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Detalhes bibliográficos
Publicado no:Oral Oncol
Main Authors: Wolf, Gregory T, Winter, William, Bellile, Emily, Nguyen, Ariane, Donnelly, CR, McHugh, Jonathan B., Thomas, Dafydd, Amlani, Lahin, Rozek, Laura, Lei, Yu L
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293994/
https://ncbi.nlm.nih.gov/pubmed/30527240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2018.10.010
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