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HISTOLOGIC PATTERN OF INVASION AND EPITHELIAL-MESENCHYMAL PHENOTYPE PREDICT PROGNOSIS IN SQUAMOUS CARCINOMA OF THE HEAD AND NECK.

INTRODUCTION: Disruption of E-cadherin function and increased expression of vimentin and the transcriptional oncogene, SOX2, are thought to characterize epithelial to mesenchymal transition (EMT) in HNSCC that contributes to invasive and metastatic behavior. To determine if such changes relate to pr...

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Dettagli Bibliografici
Pubblicato in:Oral Oncol
Autori principali: Wolf, Gregory T, Winter, William, Bellile, Emily, Nguyen, Ariane, Donnelly, CR, McHugh, Jonathan B., Thomas, Dafydd, Amlani, Lahin, Rozek, Laura, Lei, Yu L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293994/
https://ncbi.nlm.nih.gov/pubmed/30527240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2018.10.010
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