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Mind the gaps: overlooking inaccessible regions confounds statistical testing in genome analysis
BACKGROUND: The current versions of reference genome assemblies still contain gaps represented by stretches of Ns. Since high throughput sequencing reads cannot be mapped to those gap regions, the regions are depleted of experimental data. Moreover, several technology platforms assay a targeted port...
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| Udgivet i: | BMC Bioinformatics |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6293655/ https://ncbi.nlm.nih.gov/pubmed/30547739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2438-1 |
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