Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

BACKGROUND: The molecular signaling events involving in high malignancy and poor prognosis of hepatocellular carcinoma (HCC) are extremely complicated. Blockade of currently known targets has not yet led to successful clinical outcome. More understanding about the regulatory mechanisms in HCC is nec...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Dai, Bin, Zhang, Xuan, Shang, Runze, Wang, Jianlin, Yang, Xisheng, Zhang, Hong, Liu, Qi, Wang, Desheng, Wang, Lin, Dou, Kefeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293628/
https://ncbi.nlm.nih.gov/pubmed/30545369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0312-4
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