Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

BACKGROUND: The molecular signaling events involving in high malignancy and poor prognosis of hepatocellular carcinoma (HCC) are extremely complicated. Blockade of currently known targets has not yet led to successful clinical outcome. More understanding about the regulatory mechanisms in HCC is nec...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Commun Signal
Hauptverfasser: Dai, Bin, Zhang, Xuan, Shang, Runze, Wang, Jianlin, Yang, Xisheng, Zhang, Hong, Liu, Qi, Wang, Desheng, Wang, Lin, Dou, Kefeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293628/
https://ncbi.nlm.nih.gov/pubmed/30545369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0312-4
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