Improving pharmacogenetic prediction of extrapyramidal symptoms induced by antipsychotics

In previous work we developed a pharmacogenetic predictor of antipsychotic (AP) induced extrapyramidal symptoms (EPS) based on four genes involved in mTOR regulation. The main objective is to improve this predictor by increasing its biological plausibility and replication. We re-sequence the four ge...

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Bibliographic Details
Published in:Transl Psychiatry
Main Authors: Boloc, Daniel, Gortat, Anna, Cheng-Zhang, Jia Qi, García-Cerro, Susana, Rodríguez, Natalia, Parellada, Mara, Saiz-Ruiz, Jeronimo, Cuesta, Manolo J., Gassó, Patricia, Lafuente, Amalia, Bernardo, Miquel, Mas, Sergi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293322/
https://ncbi.nlm.nih.gov/pubmed/30546092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0330-4
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